Drug metabolism is best defined as?

Drug metabolism is best defined as?

• A. The chemical alteration of the drug by enzymes; primarily in the liver
• B. Removal of the drug from the body
• C. The absorption of the drug from the GI tract
• D. The distribution of the drug in tissues

Answer: (A)

Drug metabolism is the chemical change a drug undergoes due to enzymes, mainly in the liver, producing metabolites that are typically more water-soluble and easier to eliminate. This biotransformation can activate prodrugs or inactivate active drugs and helps determine how long a drug stays in the body and how it might interact with others. It’s separate from elimination (removing the drug from the body), absorption (entry from the GI tract into the bloodstream), and distribution (movement into tissues).

Drug metabolism is the chemical change a drug undergoes due to enzymes, mainly in the liver, producing metabolites that are typically more water-soluble and easier to eliminate. This biotransformation can activate prodrugs or inactivate active drugs and helps determine how long a drug stays in the body and how it might interact with others. It’s separate from elimination (removing the drug from the body), absorption (entry from the GI tract into the bloodstream), and distribution (movement into tissues).